Many also show joint and muscle tone abnormalities, including hypotonia and joint looseness in the hips. Symptoms are often similar to those of trisomy X. Other species With the Echidna , this kind of chromosomal arrangement is normal. Developmentally, people with tetrasomy X frequently show mild delays in the areas of speech development and articulation, language expression and understanding, and reading skills. Due to the variability of symptoms, some tetrasomy X girls are able to function normally, whereas others will need medical attention throughout their lives. Speech, occupational, and physical therapy may also be needed depending on the severity of the symptoms. Treatment and prognosis The general prognosis for girls with tetrasomy X is relatively good. Delays in motor development are also present, with walking ages ranging from 16 months to 4. Most girls are placed on estrogen treatment to induce breast development, arrest longitudinal growth, and stimulate bone formation to prevent osteoporosis. Medical literature reports four tetra-X pregnancies, two healthy, one with trisomy 21 , one stillborn with omphalocele. In this species genetic sex differentiation works like this: In terms of hearing, patients are more prone to ear infections , sound blockage, or nerve abnormalities.
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